GPCR
The largest family of membrane proteins in the human body and one of the most important target classes for modern drugs; approximately one-third of marketed drugs act on GPCRs.
Timeline (last 90 days)
A domestic AI drug discovery team succeeded in 18 out of 19 projects, with all 6 GPCR targets hit.
GPCRs are the largest membrane protein family in the human body, and about one-third of marketed drugs act on GPCRs.
A "hit" by an AI model on a GPCR target generally refers to the early screening or binding validation stage, and reaching a clinical candidate compound still requires drug-likeness optimization and experimental validation.
All Facts (3)
A domestic AI drug discovery team succeeded in 18 out of 19 projects, with all 6 GPCR targets hit.
50%UnverifiedGPCRs are the largest membrane protein family in the human body, and about one-third of marketed drugs act on GPCRs.
50%UnverifiedA "hit" by an AI model on a GPCR target generally refers to the early screening or binding validation stage, and reaching a clinical candidate compound still requires drug-likeness optimization and experimental validation.
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