Rosetta
A suite of physics-based modeling tools for protein structure prediction and design, performing protein modeling based on energy functions and conformational search.
Timeline (last 90 days)
Computational protein design typically relies on physics-based modeling tools such as Rosetta or diffusion models such as RFdiffusion.
macOS 27.0.1 no longer ships with Rosetta, causing Intel-based Homebrew python3 and gh to error with 'Bad CPU type'
Starting with macOS 26.4 or later, launching an app that depends on Rosetta will trigger a system notification prompting the user to update to a native version.
macOS 27 will be the last official version to support Rosetta; after that, pure Intel apps will no longer run on Apple Silicon Macs.
Apple has retained an exception for Rosetta compatibility support for legacy games that depend on Intel frameworks and are no longer maintained.
The original Rosetta was discontinued along with macOS 10.6 Snow Leopard (2009).
All Facts (6)
macOS 27 will be the last official version to support Rosetta; after that, pure Intel apps will no longer run on Apple Silicon Macs.
60%UnverifiedComputational protein design typically relies on physics-based modeling tools such as Rosetta or diffusion models such as RFdiffusion.
50%UnverifiedmacOS 27.0.1 no longer ships with Rosetta, causing Intel-based Homebrew python3 and gh to error with 'Bad CPU type'
50%UnverifiedStarting with macOS 26.4 or later, launching an app that depends on Rosetta will trigger a system notification prompting the user to update to a native version.
50%UnverifiedApple has retained an exception for Rosetta compatibility support for legacy games that depend on Intel frameworks and are no longer maintained.
50%UnverifiedThe original Rosetta was discontinued along with macOS 10.6 Snow Leopard (2009).
50%