Unverified50% confidenceFactExact time
传统分子对接方法(如AutoDock、Glide)通常假设蛋白质构象固定,仅对配体做柔性搜索
1
Sources
50%
Confidence
Long-term
Relevance
7/6/2026
First Seen
Sources
Related Claims
UnverifiedAlphaFold solved the protein folding problem that had puzzled the biology community for 50 years—namely, predicting the three-dimensional structure of a protein from its amino acid sequence—through deep learning technology.63% similarUnverifiedCo-folding refers to simultaneously predicting the three-dimensional structures of a protein and a ligand and their binding mode, allowing the protein and ligand to mutually adapt (induced fit effect).62% similar
Cite This Claim
Stable URI
https://kongchang.com/claim/114576API
curl https://kongchang.com/api/v1/knowledge/claims/114576MCP
get_claim(id=114576)